WebSolitary CHRPE. Flat round hyperpigmented lesion smooth well-defined margins. Color may be from deep brown to black. (Figure 7) A marginal depigmented halo could surround the … Webof the retina is very similar to that of solitary CHRPE; however, light and electron micros-copy have suggested that the pigment granules retain their normal ellipsoid configuration and hypertrophy and hyperplasia are not sig-nificant features [20]. Histopathologic find-ings in variants of CHRPE are summarized in Table 5.2. Clinical Features
Congenital Abnormalities of the Retinal Pigment Epithelium
WebNov 1, 1992 · This study was undertaken to determine whether the typical lesions of CHRPE, seen frequently by ophthalmologists, also were indicators of familial adenomatous polyposis. Methods Review of charts and follow-up studies were performed on all patients diagnosed and coded as having solitary CHRPE or its multifocal variant (congenital … WebNov 1, 2009 · Solitary congenital hypertrophy of the retinal pigment epithelium (CHRPE) typically is a flat, pigmented fundus lesion that was once believed to be stationary, with no potential to grow or to undergo malignant transformation. 1 More recently, however, CHRPE has been recognized to enlarge slowly in diameter in 75% to 80% of cases. 2, 3 In addition … greenlights for nonprofit success austin
Solitary congenital hypertrophy of the retinal pigment epithelium ...
WebMar 2, 2024 · Solitary CHRPE in an 11-year-old boy. (a) Optos photograph, showing the CHRPE lesion with discrete margins and adjacent retinal abnormality. (b) … WebOct 1, 2003 · The clinical records of all patients with solitary CHRPE referred to the Ocular Oncology Service at Wills Eye Hospital, Philadelphia, Pennsylvania, between January 1974 … Websolitary CHRPE that showed minimal in-crease in diameter.11-15 We recently reported 5 cases of CHRPE, each of which spawned a slowly enlarging, elevated mass that we pre-sumed to be a neoplasm of the RPE.16 At thetimeofthatreport,therewasnoavail-able histopathologic diagnosis for any of the tumors. However, in one of those pa- flying dutchman travel agency