Optimise trial hypertension

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August undefined, 2024

WebJun 1, 2024 · Observed and expected serious adverse event rates in randomised clinical trials for hypertension: an observational study comparing trials that do and do not focus on older people Article... WebThe OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE) trial will target frail individuals with polypharmacy and comorbidity, and aim to establish whether a strategy of antihypertensive medication reduction is safe and acceptable to older patients. The findings of this trial will support better patient-centred ...

OPTiMISE - OPtimising Treatment for MIld Systolic …

WebMay 26, 2009 · The current study demonstrated the efficacy and safety of treating moderate or severe hypertension with triple therapy consisting of Aml/Val/HCTZ 10/320/25 mg. Initial treatment of hypertension with a dual-combination agent with complementary mechanisms of action may allow BP goals to be realized more quickly than adding single entities … WebMar 3, 2024 · Design, Setting, and Participants The Optimising Treatment for Mild Systolic Hypertension in the Elderly (OPTIMISE) study was a randomized, unblinded, noninferiority trial conducted in 69 primary ... chipgirlhere

OPTiMISE — Oxford University - Primary Care Clinical Trials Unit

WebApr 1, 1998 · The aims are to (1) evaluate the relationship between three levels of target office diastolic blood pressure (BP) (≤80, ≤85, or ≤90 mm Hg) and cardiovascular morbidity and mortality in hypertensive patients and (2) examine the effects on cardiovascular morbidity and mortality of 75 mg aspirin daily versus placebo. WebMay 3, 2024 · While in the SEPSIPAM trial, patients with history of hypertension had lower incidence of severe acute kidney injury (AKI) in the higher target group, patients with … WebMay 26, 2024 · Design, setting, and participants: The Optimising Treatment for Mild Systolic Hypertension in the Elderly (OPTIMISE) study was a randomized, unblinded, noninferiority trial conducted in 69 primary care sites in England. Participants, whose primary care … chip g intel

Frontiers Blood Pressure Changes Following Antihypertensive ...

OPTIMISE Trial: Impact of Antihypertensive Medication Reduction …

WebJun 28, 2024 · The original SNAP-HT trial was designed to assess feasibility and safety of a self-management digital intervention in the postnatal period, but exploring the impact of the intervention on BP was an important secondary outcome. 25 The finding in SNAP-HT of a persistently lower diastolic BP at 6 months, when almost all women had stopped … chip gif makerWebMay 3, 2024 · While in the SEPSIPAM trial, patients with history of hypertension had lower incidence of severe acute kidney injury (AKI) in the higher target group, patients with history of hypertension in the 65 trial had lower 90 days mortality in the low pressure group (median MAP 65 mmHg, adjusted odds ratio, 0.67; 95% CI, 0.49–0.85). chip girl here

"WebSep 1, 2003 · According to these guidelines, supported by clinical study reports, diuretics and beta-blockers are recommended as the first-line medications in the treatment of … " - Optimise trial hypertension

Optimise trial hypertension

RPM Clinical Research – Hypertension Optimize Health

WebIn conclusion, the ACCORD BP trial evaluated the effect of targeting a systolic blood pressure of 120 mm Hg, as compared with a goal of 140 mm Hg, among patients with type 2 diabetes at high risk ... WebOPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE) The trial is funded by the National Institute for Health Research, Oxford Collaboration for Leadership …

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WebCost-effectiveness of antihypertensive deprescribing in primary care: a Markov modelling study using data from the OPTiMISE trial Sue Jowett, Shahela Kodabuckus, Gary A. Ford, F.D. Richard Hobbs, Rupert A Payne, James P. Sheppard * WebApr 20, 2024 · This study used data from the OPTiMISE trial to examine whether short-term outcomes of deprescribing vary by drug class and dose of medication withdrawn. Methods: The OPTiMISE trial included patients aged ≥80 years with controlled systolic blood pressure (SBP; <150 mmHg), receiving ≥2 antihypertensive medications. This study compared SBP ...

WebApr 20, 2024 · Methods: The OPTiMISE trial included patients aged ≥80 years with controlled systolic blood pressure (SBP; <150 mmHg), receiving ≥2 antihypertensive … WebOPTiMISE Optimising Treatment for Mild Systolic hypertension in the Elderly OPTiMISE Patient Information Leaflet V1.1 13.12.16_RCT.docx IRAS ID: 212465 Page 5 of 12 OPTiMISE trial – Full details What is the Purpose of the Trial? The population is getting older (over 3 million people in the UK are aged 80

WebJul 7, 2024 · OPTIMISE Trial: Impact of Antihypertensive Medication Reduction in Elderly Hypertensive Patients CiplaMed Home SPECIALITY General Medicine Cardiology Critical Care Medicine Dermatology Dentistry Diabetology ENT Gastroenterology & Hepatology HIV / AIDS Infectious Diseases Musculoskeletal Diseases Neuropsychiatry Obstetrics & … WebOPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE) The OPTiMISE Study The aims of this study were: To safely reduce the amount of blood …

WebThe present study tests the system's effectiveness in a randomized, controlled trial in diabetic patients with uncontrolled systolic hypertension. Of 244 subjects screened for eligibility, 110 (45%) were randomly allocated to the intervention (n = 55) or control (n = 55) group, and 105 (95.5%) completed the 1-year outcome visit.

WebSep 8, 2024 · The 2024 Optimizing Treatment for Mild Systolic Hypertension in the Elderly (OPTiMISE) trial examined the safety of reducing blood pressure medications in older … chip glassdoorWebOct 1, 2024 · The OPTiMISE trial is a multi-disciplinary and multi-institution programme of work on optimising treatment for mild systolic hypertension in the elderly. Due an ageing … granton school streathamWebThe Optimising Treatment for Mild Systolic Hypertension in the Elderly (OPTIMISE) trial used a primary care–based, randomized, unblinded, parallel group, noninferiority design. … granton school staffWebJan 23, 2024 · Welcome to the OPtimisation of Peri-operaTive CardIovascular Management to Improve Surgical outcomE II (OPTIMISE II) trial. The OPTIMISE II trial is an … chip glass baseballWebJun 3, 2024 · The OPTIMISE Randomized Clinical Trial: Deprescribing Antihypertensive Medications in Adults Aged 80 and Older and its Effect on Blood Pressure Sheppard J, et al. Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients with Hypertension Aged 80 Years and Older. grant on spey hotelsWebMay 12, 2024 · This study aimed to define the proportion and characteristics of patients eligible for hypertension trials conducted in older people. DESIGN: Cross-sectional study. SETTING: A total of 24... grant on the web epsrcWebMay 28, 2024 · The OPTIMISE (Optimising Treatment for Mild Systolic Hypertension in the Elderly) study was a randomized, unblinded, noninferiority trial conducted in 69 primary … granton to livingston